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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions ā€” written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Vitamin D deficiency history and symptoms

Introduction

Overview

Overview

Mild to moderate vitamin D deficiency could be asymptomatic in children and adults. However, severe vitamin D deficiency may be presented as rickets in children and osteomalacia in adults. Some nonspecific associated symptoms including muscle weakness or bone pain may be seen.

History

History

Obtaining the history from a patient with vitamin D deficiency is helpful in determining the cause, treatment and prevention strategy. It is essential to question about risk factors that predispose individuals to this condition. Main focuses on taking history are outlined below:[1][2][3][4][5][6][7][8][9]

  • Onset, duration, and progression of symptoms
  • Associated symptoms (muscle and bone pain)
  • History of fall
  • Malabsorption symptoms (diarrhea, weight loss, growth retardation)
  • Medications
  • Diet
  • Lifestyle
  • History of sun exposure
  • Geographic area
  • Maternal history
  • Exclusive breast-feeding
Symptoms

Symptoms

References

References

  1. ā†‘ LeFevre, Michael L. (2015). “Screening for Vitamin D Deficiency in Adults: U.S. Preventive Services Task Force Recommendation Statement”. Annals of Internal Medicine. 162 (2): 133. doi:10.7326/M14-2450. ISSNĀ 0003-4819.
  2. ā†‘ Bordelon P, Ghetu MV, Langan RC (2009). “Recognition and management of vitamin D deficiency”. Am Fam Physician. 80 (8): 841ā€“6. PMIDĀ 19835345.
  3. ā†‘ Holick MF, Chen TC (2008). “Vitamin D deficiency: a worldwide problem with health consequences”. Am. J. Clin. Nutr. 87 (4): 1080Sā€“6S. PMIDĀ 18400738.
  4. ā†‘ Holick, M. F. (2006). “Resurrection of vitamin D deficiency and rickets”. Journal of Clinical Investigation. 116 (8): 2062ā€“2072. doi:10.1172/JCI29449. ISSNĀ 0021-9738.
  5. ā†‘ Lee, Joyce M.; Smith, Jessica R.; Philipp, Barbara L.; Chen, Tai C.; Mathieu, Jeffrey; Holick, Michael F. (2016). “Vitamin D Deficiency in a Healthy Group of Mothers and Newborn Infants”. Clinical Pediatrics. 46 (1): 42ā€“44. doi:10.1177/0009922806289311. ISSNĀ 0009-9228.
  6. ā†‘ Plotnikoff GA, Quigley JM (2003). “Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain”. Mayo Clin. Proc. 78 (12): 1463ā€“70. doi:10.4065/78.12.1463. PMIDĀ 14661675.
  7. ā†‘ Holick MF (2003). “Vitamin D deficiency: what a pain it is”. Mayo Clin. Proc. 78 (12): 1457ā€“9. doi:10.4065/78.12.1457. PMIDĀ 14661673.
  8. ā†‘ Hicks, Gregory E.; Shardell, Michelle; Miller, Ram R.; Bandinelli, Stefania; Guralnik, Jack; Cherubini, Antonio; Lauretani, Fulvio; Ferrucci, Luigi (2008). “Associations Between Vitamin D Status and Pain in Older Adults: The Invecchiare in Chianti Study”. Journal of the American Geriatrics Society. 56 (5): 785ā€“791. doi:10.1111/j.1532-5415.2008.01644.x. ISSNĀ 0002-8614.
  9. ā†‘ Holick, Michael F.; Binkley, Neil C.; Bischoff-Ferrari, Heike A.; Gordon, Catherine M.; Hanley, David A.; Heaney, Robert P.; Murad, M. Hassan; Weaver, Connie M. (2011). “Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline”. The Journal of Clinical Endocrinology & Metabolism. 96 (7): 1911ā€“1930. doi:10.1210/jc.2011-0385. ISSNĀ 0021-972X.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]