Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Williams-Campbell syndrome
Introduction
Synonyms and keywords: Cartilage deficiency
Overview
Overview
Williams–Campbell syndrome is a disease of the airways where cartilage in the bronchi is defective. This leads to collapse of the airways and bronchiectasis.[1] Williams–Campbell syndrome is deficiency of the bronchial cartilage distally.[2]
Historical Perspective
Historical Perspective
It was described in 1960 by Howard Williams and Peter Campbell.[3][4]
Diagnosis
Diagnosis
Radiologically, the lungs are overinflated and on bronchoscopy, bronchomalacia is demonstrated.[2]
References
References
- ↑ Palmer, S. M.; Layish, D. T.; Kussin, P. S.; Tapson, V. F.; Oury, T.; Davis, R. D. (1998). “Lung Transplantation for Williams-Campbell Syndrome”. Chest. 113 (2): 534–7. doi:10.1378/chest.113.2.534. PMID 9498979.
- ↑ 2.0 2.1 2.2 2.3 2.4 british medical journal (BMJ)
- ↑ Williams, H; Campbell, P (April 1960). “Generalized Bronchiectasis associated with Deficiency of Cartilage in the Bronchial Tree”. Arch. Dis. Child. 35 (180): 182–91. doi:10.1136/adc.35.180.182. PMC 2012546. PMID 13844857.
- ↑ Jones, VF; Eid, NS; Franco, SM; Badgett, JT; Buchino, JJ (1993). “Familial congenital bronchiectasis: Williams-Campbell syndrome”. Pediatric pulmonology. 16 (4): 263–7. doi:10.1002/ppul.1950160410. PMID 8265276.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]