Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
High chylomicron remnant causes
Introduction
Overview
Overview
High chylomicron remnants level can either be due to genetic conditions as in type I and type V hyperlipoproteinemia or can be secondary to conditions such as chronic renal failure, hypothyroidism, and diabetes mellitus.
Causes
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Alcoholism
- Chronic renal failure
- Diabetes mellitus
- Hypothyroidism
- Oral contraceptives
- Pregnancy
- Thiazide diuretics
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Antiretroviral therapy, atypical antipsychotics, glucocorticoids, heparin, isotretinoin, oral contraceptives, tamoxifen, thiazide diuretics |
| Ear Nose Throat | No underlying causes |
| Endocrine | Diabetes mellitus, hypothyroidism |
| Environmental | No underlying causes |
| Gastroenterologic | Acute pancreatitis, alcoholic liver disease, cirrhosis, hepatitis, hereditary hemochromatosis, non-alcoholic steatohepatitis (NASH), Wilson’s disease |
| Genetic | Familial hypertriglyceridemia, fructose-1-phosphate aldolase deficiency, galactosemia, glycogen storage disease type I, glycogen storage disease type IV, lipoprotein lipase deficiency, mixed hyperlipoproteinemia, type 1C hyperlipoproteinemia, tyrosinemia type 1 |
| Hematologic | No underlying causes |
| Iatrogenic | Dialysis |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | Familial hypertriglyceridemia, glycogen storage disease type I, glycogen storage disease type IV, high carbohydrate diet, high saturated fat diet, isolated low HDL, lipoprotein lipase deficiency |
| Obstetric/Gynecologic | Pregnancy |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | Acute renal failure, chronic renal failure, nephrotic syndrome |
| Rheumatology/Immunology/Allergy | Autoimmune hyperchylomicronemia [1] |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | Alcoholism |
Causes by Alphabetical Order
References
References
- ↑ 1.0 1.1 Yoshimura, T.; Ito, M.; Sakoda, Y.; Kobori, S.; Okamura, H. (1998). “Rare case of autoimmune hyperchylomicronemia during pregnancy”. Eur J Obstet Gynecol Reprod Biol. 76 (1): 49–51. PMID 9481547. Unknown parameter
|month=ignored (help) - ↑ Weintraub M, Burstein A, Rassin T, Liron M, Ringel Y, Cabili S; et al. (1992). “Severe defect in clearing postprandial chylomicron remnants in dialysis patients”. Kidney Int. 42 (5): 1247–52. PMID 1453610.
- ↑ Ito M, Takamatsu J, Matsuo T, Kameoka K, Kubota S, Fukata S; et al. (2003). “Serum concentrations of remnant-like particles in hypothyroid patients before and after thyroxine replacement”. Clin Endocrinol (Oxf). 58 (5): 621–6. PMID 12699445.
- ↑ Benjó AM, Maranhão RC, Coimbra SR, Andrade AC, Favarato D, Molina MS; et al. (2006). “Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol: effects of niacin treatment”. Atherosclerosis. 187 (1): 116–22. doi:10.1016/j.atherosclerosis.2005.08.025. PMID 16458316.
- ↑ Brasaemle DL, Cornely-Moss K, Bensadoun A (1993). “Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E.” J Lipid Res. 34 (3): 455–65. PMID 8468529.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mugilan Poongkunran M.B.B.S [2]