
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Gallbladder volvulus
Introduction
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Synonyms and keywords: Torsion of gallbladder
Overview
Overview
Volvulus is twisting of a non solid organ around its mesentric axis. Gallbladder volvulus is twisting or rotation of the gallbladder along the axis of the cystic duct and vascular pedicle (cystic artery).[1]
Historical Perspective
It was first described by Wendal in 1898.
Pathophysiology
Torsion of gall bladder leads to occlusion of the cystic duct and the cystic artery. This torsion can be complete (180o – 360o) or incomplete (< 180o). Incomplete torsion causes obstruction of the bile duct and vascular supply may be spared. In complete obstruction both are compromised. This occlusion leads to an increased amount of bile in the lumen and a decreased flow of blood to the organ. Increased pressure in the lumen with ischemia leads to acute inflammation causing a surgical emergency.
Diagnosis
History and Symptoms
Presentation of gallbladder volvulus is very non -specific. It is tough to diagnose based upon just the history and symptoms because patients present with acute abdominal pain with or without vomiting. At times there may be a tender mobile mass palpated suggestive of a floating gallbladder.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Historical Perspective
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Overview
It was first described by Wendal in 1898.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Pathophysiology
Overview
Torsion of gall bladder leads to occlusion of the cystic duct and the cystic artery. This torsion can be complete (180o – 360o) or incomplete (< 180o). Incomplete torsion causes obstruction of the bile duct and vascular supply may be spared. In complete obstruction both are compromised. This occlusion leads to an increased amount of bile in the lumen and a decreased flow of blood to the organ. Increased pressure in the lumen with ischemia leads to acute inflammation causing a surgical emergency.
Pathophysiology
Gross Pathology
- Enlarged and distended gallbladder.
- Torsion along the long axis of the peduncle.
- Thick edematous wall with mucosal congestion.
Microscopic Pathology
- Extensive necrosis of the wall.[1]
- Findings may be similar to gangrenous cholecystitis due to severe ischemia.
- The GB wall shows almost complete coagulation necrosis with intramural hemorrhages.
- A thin layer of degenerated collagen ο¬ber, derived from the mucosa and proper muscle, may be seen along the inner side, and a thin subserosal connective tissue layer may seen along the outermost side.
References
- β Aibe H, Honda H, Kuroiwa T, Yoshimitsu K, Irie H, Shinozaki K; et al. (2002). “Gallbladder torsion: case report”. Abdom Imaging. 27 (1): 51β3. PMIDΒ 11740608.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Causes
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Causes
Volvulus of gallbladder is known to be caused due to:[1]
- Inherent causes
- Floating gallbladder
- Acquired causes
- Splanchnoptosis
- Senile humpback
- Physical causes
- Sudden changes of intraperitoneal pressure
- Sudden changes of body position
- Hyperperistalsis of organs near the gallbladder
- Trauma to the abdomen
References
- β Kimura Y, Takada T, Kawarada Y, Nimura Y, Hirata K, Sekimoto M; et al. (2007). “Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines”. J Hepatobiliary Pancreat Surg. 14 (1): 15β26. doi:10.1007/s00534-006-1152-y. PMCΒ 2784509. PMIDΒ 17252293.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Differentiating Gallbladder Volvulus from other Diseases
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Differentiating Gallbladder Volvulus from other Diseases
- Careful evaluation is important to rule out other causes of jaundice that argue against the diagnosis.
- Absence of toxemia
- Poor response to antibiotic therapy
- Ultrasound or other imaging studies help in differentiating gallbladder volvulus from other causes.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Epidemiology and Demographics
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Epidemiology and Demographics
Over 500 cases have been documented since its description in 1898.[1]
Age
- There are very few cases reported in the pediatric population.
- 85% of the cases are reported in 60 – 80 age group.
Gender
References
- β Janakan G, Ayantunde AA, Hoque H (2008). “Acute gallbladder torsion: an unexpected intraoperative finding”. World J Emerg Surg. 3: 9. doi:10.1186/1749-7922-3-9. PMCΒ 2266718. PMIDΒ 18294374.
- β Tarhan OR, Barut I, Dinelek H (2006). “Gallbladder volvulus: review of the literature and report of a case”. Turk J Gastroenterol. 17 (3): 209β11. PMIDΒ 16941256.
- β Stieber AC, Bauer JJ (1983). “Volvulus of the gallbladder”. Am J Gastroenterol. 78 (2): 96β8. PMIDΒ 6823944.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Risk Factors
Risk Factors
Risk factors for gallbladder volvulus include[1]:
- Constipation
- Hyperperistalsis
- Multiparity
- Scoliosis
- Weight loss
The role of cholelithiasis as a risk factor is uncertain.
References
- β Taziaux P, Pans A, Lismonde M, Namur M, Hermans G, Wahlen C (1990). “[Gallbladder volvulus]”. J Chir (Paris). 127 (8β9): 408β11. PMIDΒ 2229215.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Natural History, Complications and Prognosis
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Complications
- Acute perforation
- Bilious peritonitis
- Bowel adhesion
- Gallbladder necrosis
- Gangrenous cholecystitis
- Sepsis
Prognosis
- It has a favorable prognosis due to early diagnosis and prompt treatment.
- With immediate surgery the mortality rate is less than 5%.[1][2]
References
- β Shaikh AA, Charles A, Domingo S, Schaub G (2005). “Gallbladder volvulus: report of two original cases and review of the literature”. Am Surg. 71 (1): 87β9. PMIDΒ 15757065.
- β Chiow AK, Ibrahim S, Tay KH (2007). “Torsion of the gallbladder: a rare entity”. Ann Acad Med Singapore. 36 (8): 705β6. PMIDΒ 17767346.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
