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Ovarian torsion

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Adnexal torsion

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ovarian torsion refers to a twisting of the ovary. If the torsion involves the ovary and the oviduct it is called adnexal torsion. Ovarian torsion is in the differential diagnosis of unilateral abdominal pain in a woman. Approximately 60% of the time it occurs on the right side of the abdomen.

Epidemiology and Demographics

Obviously ovarian torsion only occurs in women. Ovarian torsion is the fifth most common gynecologic emergency. 83% of cases occur in women of reproductive age, with a median age at presentation of 28 years.

Diagnosis

History and Symptoms

Patients with ovarian torsion often present with sudden onset of sharp and usually unilateral lower abdominal pain. 70% of the cases are accompanied by nausea and vomiting. In case of necrosis, fever occurs.

Ultrasound

Abdominal ultrasound is helpful in establishing the diagnosis in patients with suspected torsion.

Treatment

Medical Therapy

Associated symptoms of nausea and vomiting can be treated with antiemetics. Dehydration secondary to vomiting can be treated with intravenous fluids.

Surgery

Conservative treatment of ovarian torsion includes laparoscopy to uncoil the torsed ovary and possibly oophoropexy to fixate the ovary which is likely to torse again. In severe cases, where blood flow is cut off to the ovary for an extended period of time, necrosis of the ovary can occur. In these cases the ovary must be surgically removed.

References


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Historical Perspective

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References


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Pathophysiology

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Causes

Overview

Life Threatening Causes

Common Causes

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Urofollitropin, choriogonadotropin alfa
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References


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Differentiating Ovarian Torsion from other Conditions

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: vSyed Hassan A. Kazmi BSc, MD [2]

Overview

Prostatitis should be differentiated from other conditions presenting with lower abdominal pain, nausea and vomiting.

Differentiating Ovarian Torsion from other Diseases

Prostatitis should be differentiated from other conditions presenting with lower abdominal pain, nausea and vomiting. The differentials include the following:[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]


Category Disease History Signs and Symptoms Physical Examination Laboratory abnormalities
Nausea/vomiting Hematuria Location of pain Fever Tachycardia Hypotension Hypertension Anorexia Constipation Rebound abdominal tenderness Urinary frequency/Urgency/Dysuria Costovetebral angle tenderness Pelvic Examination Rectal Examination Complete Blood Count (CBC) Urinalysis BUN Creatinine Stone analysis Urine Beta- hCG Abnormal Liver Function Tests (LFTs) Serum Amylase/Lipase Abdominal/Pelvic CT scan Serum Parathyroid hormone levels (PTH)

Renal Pathology

Nephrolithiasis + + + +/- +
  • Non-contrast CT scan may show stone as radiolucency
+/-
Pyelonephritis + + (microscopic) + + + +/- + + +
  • Globaly decreased contrast uptake
  •  Foci from abscess pockets
Renal infarct + + + + +
Renal papillary necrosis + (microscopic) + +/- + +
Renal cell carcinoma + + (microscopic) + + +/-
  • Anemia
  • Non-contrast CT:
  • Contrast-enhanced:
    • Homogenous (small lesions) to irregular (large lesions) contrast enhancement
Uretral stricture +/- +

Gynecological Pathology

Pelvic inflammatory disease
  • Right/left upper quadrant
+ + + + +
  • Thickening of the uterosacral ligaments
  • Haziness of the pelvic fat
  • Periovarian stranding
  • Enhancement of the adjacent peritoneum
  • Thick-walled, complex fluid collection with septa formation (abscess pockets)
Ovarian torsion
  • Sudden acute pain
  • Sharp pain aggravated by walking
  • Intermittent/colicky pain
+ +
  • Twisted ovarian pedicle
  • Enlarged ovary (>4.0 cm)
  • Distended pedicle
  • Possible underlying ovarian lesion
Ectopic pregnancy + + + + (if ruptured) +
  • Low platelet distribution width (decreased platelet activation)
  • Monocytosis
+ +/- N/A

Abdominal Pathology

Cholecystitis + + + + + +/-
  • Gallbladder distention
  • Wall thickening
  • Mucosal hyperenhancement,
  • Pericholecystic fat stranding or fluid
  • Gallstones
Appendicitis + + + + + +/-
  • Leukocytosis
+ (if perforation)
Diverticulitis + + + + + + (if perforation)
  • Colonic wall thickening (wall thickness is greater than 3 mm on the short axis of the lumen)
  • Pericolic fat stranding
Abdominal aortic aneurysm + + + (if rupture)
  • Ultrasound more sensitive than CT scan
  • CT scan may accurately predict the aneurysmal size
  • Helical CT has faster scanning time (30 to 60 seconds) and the ability to obtain all images in one breath hold
Portal vein thrombosis + + + + + + (if bowel ischemia or infarction-secondary to extension of thrombus to superior mesenteric vein) + + (if bowel infarction, perforation)
  • On non-contrast CT:
    • Hyperdense thrombus
  • On contrast CT
    • Non-enhancing defect of bland thrombus
    • Tumor thrombus exhibits enhancement
Duodenal ulcer + + + + + (if perforation) + (if bowel perforation)
Ischemic colitis + + + + (if necrosis and sepsis) + + + + (if transmural necrosis) + (if bowel perforation)

References

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  2. Semins MJ, Matlaga BR (February 2010). “Medical evaluation and management of urolithiasis”. Ther Adv Urol. 2 (1): 3–9. doi:10.1177/1756287210369121. PMC 3126068. PMID 21789078.
  3. Venkatesh L, Hanumegowda RK (June 2017). “Acute Pyelonephritis – Correlation of Clinical Parameter with Radiological Imaging Abnormalities”. J Clin Diagn Res. 11 (6): TC15–TC18. doi:10.7860/JCDR/2017/27247.10033. PMC 5535453. PMID 28764263.
  4. Garin EH, Olavarria F, Araya C, Broussain M, Barrera C, Young L (July 2007). “Diagnostic significance of clinical and laboratory findings to localize site of urinary infection”. Pediatr. Nephrol. 22 (7): 1002–6. doi:10.1007/s00467-007-0465-7. PMID 17375337.
  5. Lee DG, Jeon SH, Lee CH, Lee SJ, Kim JI, Chang SG (April 2009). “Acute pyelonephritis: clinical characteristics and the role of the surgical treatment”. J. Korean Med. Sci. 24 (2): 296–301. doi:10.3346/jkms.2009.24.2.296. PMC 2672131. PMID 19399273.
  6. Saeed K (2012). “Renal infarction”. Int J Nephrol Renovasc Dis. 5: 119–23. doi:10.2147/IJNRD.S33768. PMC 3437809. PMID 22969301.
  7. Mahamid M, Francis A, Abid A, Awawde M, Abu-Elhija O (2014). “Embolic renal infarction mimicking renal colic”. Int J Nephrol Renovasc Dis. 7: 157–9. doi:10.2147/IJNRD.S59745. PMC 4011809. PMID 24812524.
  8. Korzets Z, Plotkin E, Bernheim J, Zissin R (October 2002). “The clinical spectrum of acute renal infarction”. Isr. Med. Assoc. J. 4 (10): 781–4. PMID 12389340.
  9. Brix AE (2002). “Renal papillary necrosis”. Toxicol Pathol. 30 (6): 672–4. doi:10.1080/01926230290166760. PMID 12512867.
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  11. Ng CS, Wood CG, Silverman PM, Tannir NM, Tamboli P, Sandler CM (October 2008). “Renal cell carcinoma: diagnosis, staging, and surveillance”. AJR Am J Roentgenol. 191 (4): 1220–32. doi:10.2214/AJR.07.3568. PMID 18806169.
  12. Ares Valdés Y, Amador Sandoval B, Morales JC, Alonso Domínguez F, Carballo Velásquez L, Fragas Valdés R, Shou Rodríguez A (September 2004). “[The role of CT scan in the diagnosis of renal cell carcinoma]”. Arch. Esp. Urol. (in Spanish; Castilian). 57 (7): 737–42. PMID 15536955.
  13. Leveridge MJ, Bostrom PJ, Koulouris G, Finelli A, Lawrentschuk N (June 2010). “Imaging renal cell carcinoma with ultrasonography, CT and MRI”. Nat Rev Urol. 7 (6): 311–25. doi:10.1038/nrurol.2010.63. PMID 20479778.
  14. Tritschler S, Roosen A, Füllhase C, Stief CG, Rübben H (March 2013). “Urethral stricture: etiology, investigation and treatments”. Dtsch Arztebl Int. 110 (13): 220–6. doi:10.3238/arztebl.2013.0220. PMC 3627163. PMID 23596502.
  15. Mundy AR, Andrich DE (January 2011). “Urethral strictures”. BJU Int. 107 (1): 6–26. doi:10.1111/j.1464-410X.2010.09800.x. PMID 21176068.
  16. Maciejewski C, Rourke K (February 2015). “Imaging of urethral stricture disease”. Transl Androl Urol. 4 (1): 2–9. doi:10.3978/j.issn.2223-4683.2015.02.03. PMC 4708283. PMID 26816803.
  17. Soper DE (August 2010). “Pelvic inflammatory disease”. Obstet Gynecol. 116 (2 Pt 1): 419–28. doi:10.1097/AOG.0b013e3181e92c54. PMID 20664404.
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  20. Eggert J, Sundquist K, van Vuuren C, Fianu-Jonasson A (October 2006). “The clinical diagnosis of pelvic inflammatory disease–reuse of electronic medical record data from 189 patients visiting a Swedish university hospital emergency department”. BMC Womens Health. 6: 16. doi:10.1186/1472-6874-6-16. PMC 1624808. PMID 17054801.
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Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Obviously ovarian torsion only occurs in women. Ovarian torsion is the fifth most common gynecologic emergency. 83% of cases occur in women of reproductive age, with a median age at presentation of 28 years.

References


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Risk Factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Risk Factors

  • Infertility drugs

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Natural History, Complications and Prognosis

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Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case #1

Related Chapters


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