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Blind loop syndrome

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]

Synonyms and keywords: Stagnant loop syndrome

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]


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Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

Blind loop syndrome occurs when digested food slows or stops moving through part of the intestines, which leads to overgrowth of bacteria in the intestines, causing problems with absorbing nutrients.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Blind loop syndrome overview from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

References

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Historical Perspective

Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur

Historical Perspective

Discovery

  • In 1924, Seyderhelm and others were able to produce artificially ahyperchromic anemia in dogs, who hadintestinal stricture and they could relate this anemia to the infection of the intestine. So, this is probably the earliest studies to have established absorption defects in blind loop syndrome, caused by infection.[1]


References

  1. STARZL TE, BUTZ GW, HARTMAN CF (November 1961). “The blind-loop syndrome after gastric operations”. Surgery. 50: 849–58. PMC 2981163. PMID 13916392.


Classification

Overview


Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

It is divided into 3 types depending on the type of resection.

Classification

Blind loop syndrome ( short bowel syndrome) occurring after surgicalresection can be classified into 3 types depending on the type of resection.

Type 1:
Type 2:
Type 3:


References


Pathophysiology

Overview


Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

Pathophysiology

Physiology

The overgrowth of the bacteria in the intestine is prevented by the constant peristaltic movements of the bowel, and also by the presence of chemicals like gastric secretions, bile and pancreatic secretions.

Pathogenesis:

Whenever there is obstruction to the constant peristaltic movements of the small intestine, either due toanatomical causes, surgical causes or physiological causes, it causes stagnation of the bowel contents, bacterial overgrowth in the small intestine leading to blind loop syndrome.

Due to the stagnation and decreased peristaltic movements, the digestive processes are disrupted, leading to malabsorption of bile salts, fat, fat soluble vitamins,carbohydrates, proteins.


Associated Conditions

Conditions associated with blind loop syndrome include:

Gross Pathology

On gross pathology, distension of the bowl loop can be seen in the blind loop syndrome.

Microscopic Pathology

On microscopic histo pathological analysis, there can be injury to the intestinal wall.


Pathophysiology

The obstruction of a section of intestine causes ineffective bile salt mediated digestion of fats, causing fatty stools and poor absorption of fat andfat-soluble vitamins. CyanocobalaminVitamin B12 deficiency may occur because the increased bacterial population can consume the vitamin.

References

Causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]

Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

The causes can be divided into medical causes and Surgical causes.

Causes

The name of this condition refers to the “blind loop” formed by the blocked intestine. This blind loop does not allow the normal flow of digested food through the intestinal tract.

  • after many operations, including subtotal gastrectomy.[1]
  • operations for extreme obesity
  • .as a complication of inflammatory bowel disease,celiac disease,radiation enteritis
  • Diabetes
  • Scleroderma
  • Small bowel diverticulosis

References

  1. Sandrasegaran K, Maglinte DD, Rajesh A, Tann M, Kopecky KK (January 2006). “CT findings for postsurgical blind pouch of small bowel”. AJR Am J Roentgenol. 186 (1): 110–3. doi:10.2214/AJR.04.1628. PMID 16357387.

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Differentiating Blind loop syndrome from other Diseases

Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

Differentiating [Disease name] from other Diseases


Blind loop syndrome should be differentiated from other diseases causing mal absorption, nutritional imbalances.

Differential Diagnosis:

References


Epidemiology and Demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]


Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

Epidemiology and Demographics

Afferent limb syndrome is one of the cause of blind loop syndrome, and is commonpostoperative complication. One study has estimated that it occurs in 13% of postpancreatico duodenectomy patients.

Afferent limb syndrome has decreased in incidence after introduction of newer surgical techniques.

References


Risk Factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]


Overview

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

There are many risk factors which can cause blind loop syndrome. All the factors which can cause disorders in motility can cause blind loop syndrome.

Risk Factors

References

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Screening

Overview

There is insufficient evidence to recommend routine screening for blind loop syndrome.

Screening

There is insufficient evidence to recommend routine screening for blind loop syndrome.

References


Natural History, Complications and Prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]


Overview

Natural History, Complications, and Prognosis

Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.

If left untreated, almost all patients will develop nutritional deficiencies.

Natural History

If left untreated, almost all the patients withblind loop syndrome may lead to poor nutrition. Blind loop syndrome can cause loss of vitamins and minerals, including vitamin B12.

Complications

Prognosis

Majority of the patients get better with antibiotics and nutritional supplements.

If surgery is required, and patient undergoes surgery for the condition, then the prognosis is very good.

References


Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Abdominal X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy

Case Studies

Case Studies

Case #1


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