Blind loop syndrome
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
Synonyms and keywords: Stagnant loop syndrome
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
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Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
Blind loop syndrome occurs when digested food slows or stops moving through part of the intestines, which leads to overgrowth of bacteria in the intestines, causing problems with absorbing nutrients.
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Blind loop syndrome overview from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
Historical Perspective
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur
Historical Perspective
Discovery
- In 1924, Seyderhelm and others were able to produce artificially ahyperchromic anemia in dogs, who hadintestinal stricture and they could relate this anemia to the infection of the intestine. So, this is probably the earliest studies to have established absorption defects in blind loop syndrome, caused by infection.[1]
References
Classification
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
It is divided into 3 types depending on the type of resection.
Classification
Blind loop syndrome ( short bowel syndrome) occurring after surgicalresection can be classified into 3 types depending on the type of resection.
Type 1:
- afterJejunostomy (end jejunostomy)
- Common reason
- dehydration starts immediately after surgery
Type 2:
- occurs afterJejunocolic anastomosis
- weight loss andnutrition abnormalities occur after months
Type 3:
- occurs afterJejunoileal anastomosis
- weight loss andnutritional abnormalities occur after months
References
Pathophysiology
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
Pathophysiology
Physiology
The overgrowth of the bacteria in the intestine is prevented by the constant peristaltic movements of the bowel, and also by the presence of chemicals like gastric secretions, bile and pancreatic secretions.
Pathogenesis:
Whenever there is obstruction to the constant peristaltic movements of the small intestine, either due toanatomical causes, surgical causes or physiological causes, it causes stagnation of the bowel contents, bacterial overgrowth in the small intestine leading to blind loop syndrome.
Due to the stagnation and decreased peristaltic movements, the digestive processes are disrupted, leading to malabsorption of bile salts, fat, fat soluble vitamins,carbohydrates, proteins.
Associated Conditions
Conditions associated with blind loop syndrome include:
Gross Pathology
On gross pathology, distension of the bowl loop can be seen in the blind loop syndrome.
Microscopic Pathology
On microscopic histo pathological analysis, there can be injury to the intestinal wall.
Pathophysiology
The obstruction of a section of intestine causes ineffective bile salt mediated digestion of fats, causing fatty stools and poor absorption of fat andfat-soluble vitamins. CyanocobalaminVitamin B12 deficiency may occur because the increased bacterial population can consume the vitamin.
References
Causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
The causes can be divided into medical causes and Surgical causes.
Causes
The name of this condition refers to the “blind loop” formed by the blocked intestine. This blind loop does not allow the normal flow of digested food through the intestinal tract.
- after many operations, including subtotal gastrectomy.[1]
- operations for extreme obesity
- .as a complication of inflammatory bowel disease,celiac disease,radiation enteritis
- Diabetes
- Scleroderma
- Small bowel diverticulosis
References
- ↑ Sandrasegaran K, Maglinte DD, Rajesh A, Tann M, Kopecky KK (January 2006). “CT findings for postsurgical blind pouch of small bowel”. AJR Am J Roentgenol. 186 (1): 110–3. doi:10.2214/AJR.04.1628. PMID 16357387.
Differentiating Blind loop syndrome from other Diseases
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
Differentiating [Disease name] from other Diseases
Blind loop syndrome should be differentiated from other diseases causing mal absorption, nutritional imbalances.
Differential Diagnosis:
- Inflammatory bowel disease
- Diverticulosis
- Bowel obstruction
- Irritable bowel syndrome
- Malabsorption–Celiac disease
References
Epidemiology and Demographics
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
Epidemiology and Demographics
Afferent limb syndrome is one of the cause of blind loop syndrome, and is commonpostoperative complication. One study has estimated that it occurs in 13% of postpancreatico duodenectomy patients.
Afferent limb syndrome has decreased in incidence after introduction of newer surgical techniques.
References
Risk Factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
There are many risk factors which can cause blind loop syndrome. All the factors which can cause disorders in motility can cause blind loop syndrome.
Risk Factors
- Abdominal surgeries
- Gynecological surgeries
- Inflammatory bowel disease
- Diabetes
- Scleroderma
- injury in theintestinal wall.
References
Screening
Overview
There is insufficient evidence to recommend routine screening for blind loop syndrome.
Screening
There is insufficient evidence to recommend routine screening for blind loop syndrome.
References
Natural History, Complications and Prognosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaik Aisha sultana, [2]
Overview
Natural History, Complications, and Prognosis
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
If left untreated, almost all patients will develop nutritional deficiencies.
Natural History
If left untreated, almost all the patients withblind loop syndrome may lead to poor nutrition. Blind loop syndrome can cause loss of vitamins and minerals, including vitamin B12.
Complications
- Complete intestinal obstruction
- Intestinal infarction (death of intestine)
- Perforation (hole) of intestine
- malabsorption and malnutrition
Prognosis
Majority of the patients get better with antibiotics and nutritional supplements.
If surgery is required, and patient undergoes surgery for the condition, then the prognosis is very good.
References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Abdominal X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy
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