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MyEClinic
MyEClinic
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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Intercostal muscle spasm

Introduction

Synonyms and keywords: Muscle pain; myodynia

Overview

Overview

Overview

Myalgia means “muscle pain” and is a symptom of many diseases and disorders. The most common cause for myalgia is either overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or chronic fatigue syndrome.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Pathophysiology

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References

Causes

Causes

Overview

The most common causes of myalgia are overuse, injury or stress[1]. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes.

Causes

Common Causes

Causes by Organ System

Cardiovascular Cholesterol embolism, Claudication, Endocarditis, Exercise intolerance, Hemochromatosis, Polyarteritis nodosa, Vasculitis
Chemical/Poisoning 5-azacytidine, Aluminium toxicity, Arsenic trioxide, Lead, Nitrogen dioxide, Tryptophan
Dental No underlying causes
Dermatologic Dermatomyositis, Ehlers-danlos syndrome, Morphea, Sweet’s disease, Weber-christian disease 
Drug Side Effect Acetaminophen, Acrylamide, Aldara , Amlodipine besylate , Amphotericin b, Aromatase inhibitors, Artemether, Atorvastatin calcium trihydrate, Atovaquone, Bezafibrate, Bicalutamide, Boniva, Campylobacter jejuni, Carfilzomib, Ciprofloxacin , Cytarabine, Dabrafenib, Darbepoetin, Desloratadine, Disoproxil fumarate, Efavirenz, Emtricitabine, Enzalutamide, Eribulin, Evolocumab, Filgastrim, Florbetapir f-18, Fulvestrant, Gemifloxacin mesylate, Glucocorticoid-induced myopathy, Hpv vaccine, Idursulfase, Imatinib mesylate, Infliximab, Interferon alfa-2b , Interferon alpha, Interferon beta- 1a, Interferon beta- 1b, Interferon gamma, Interleukin 2, Isotretinoin, Ivacaftor, Ixabepilone, Janumet, Leflunomide, Lenvatinib, Letrozole, Levalbuterol, Linagliptin, Melarsoprol, Mifepristone, Nabilone, Nalmefene, Naltrexone, Nevirapine, Niacin, Norfloxacin, Olaratumab, Oprelvekin, Oxycodone, Paclitaxel, Pegylated interferon alfa-2a, Pentamidine isethionate, Pergolide, Pertuzumab, Pravastatin, Procainamide, Progesterone, Quinupristin, Reslizumab, Rhinovirus infection, Rifaximin, Rizatriptan, Rosuvastatin, Sertraline, Simvastatin, Sipuleucel-t, Sofosbuvir, Sonidegib, Sorafenib, Spiriva, Statins, Sumatriptan, Suxamethonium, Telbivudine, Tenofovir, Tesamorelin, Thalidomide, Trametinib dimethyl sulfoxide, Trastuzumab, Triptorelin pamoate, Valdecoxib, Vardenafil, Vytorin, Zetia, Zomig, Zonisamide
Ear Nose Throat No underlying causes
Endocrine Adrenal insufficiency, Chronic fatigue syndrome, Hypothyroid myopathy, Thyroid disease
Environmental No underlying causes
Gastroenterologic Barcoo fever, Febuxostat, Glycogenosis type 5, Glycogenosis type 7, Glycogenosis type 9d, Hemochromatosis, Muscle glycogen synthase deficiency, Norwalk gastroenteritis , Prostatitis, Toxoplasmosis, Viral digestive infections 
Genetic Channelopathy, Ehlers-danlos syndrome, Glycogenosis type 5, Glycogenosis type 7, Glycogenosis type 9d, Hanac syndrome, Mercaptopropionylglycine, Muscle glycogen synthase deficiency, Myalgic encephalomyelitis, Myoadenylate deaminase deficiency, Nalp12-associated hereditary periodic fever syndrome, Phosphogylcerate mutase 2 deficiency, West nile fever
Hematologic Babesiosis , Blood transfusion , Carnitine palmitoyltransferase ii deficiency, Enolase deficiency type 3 , Enterohemorrhagic escherichia coli infection, Hematoma, Hemorrhagic fever, Hypokalemia, Lactate dehydrogenase-a deficiency, Lassa fever, Paroxysmal cold haemoglobinuria, Phosphogylcerate mutase 2 deficiency, Postoperative septicaemia , Severe potassium deficiency, Toxemia , Toxic shock syndrome, Viral hemorrhagic fever, Vitamin d deficiency
Iatrogenic Hpv vaccine
Infectious Disease Acute posterior multifocal placoid pigment , Aids, Babesiosis , Barcoo fever, Bartonellosis , Benzodiazepine withdrawal, Blastomycosis , Bornholm disease, Brucellosis, Chikungunya, Coccidioidomycosis , Common cold, Delayed viral syndromes , Dengue fever, Ebola, Ehrlichia ewingii, Endemic typhus, Enterohemorrhagic escherichia coli infection, Epidemic typhus , Epstein-barr virus, Familial mediterranean fever, Filovirus , Flavivirus , Flu , Granulocyte-macrophage colony stimulating factor, Hantavirus , Heartland virus, Hemorrhagic fever, Herpes, Hibernian fever, Histoplasmosis, Hiv, Human granulocytic ehrlichiosis, Human parvovirus b19 infection , Infectious diarrhea , Infectious mononucleosis, Influenza, Lassa fever, Legionellosis, Leptospirosis, Lyme disease, Malaria , Marburg virus , Mastocytosis, Meningitis, Meningococcal disease , Monkeypox, Muscle abscess, Pharyngitis, Pneumonia, Polio, Postoperative septicaemia , Prostatitis, Psittacosis, Pyomyositis, Q fever , Queensland tick typhus, Rabies, Rickettsia akari, Rickettsia siberica , Rickettsia typhi , Rickettsial disease , Ricketttsialpox , Rift valley fever, Rocky mountain spotted fever, Ross river virus, Roundworm , Sargramostim, Schistosoma haematobium, Sepsis , Spotted fevers , Staphylococcal toxic shock syndrome, Staphylococcus aureus, Streptococcal infections, Tick typhus, Toxemia , Toxic shock syndrome, Toxoplasmosis, Trichinella spiralis, Trichinosis , Typhoid fever , Vibrio vulnificus infection , Viral digestive infections , Viral hemorrhagic fever, Viral pneumonia, Weil’s syndrome , West nile encephalitis, West nile fever, Western equine encephalitis, Wuchereria bancrofti, Yellow fever
Musculoskeletal/Orthopedic Bursitis, Caveolin-3 related distal myopathy, Delayed onset muscle soreness, Fibromyalgia, Hypothyroid myopathy, Hypotonia, Inflammatory myopathy, Muscle abscess, Myoadenylate deaminase deficiency, Myopathy , Myositis, Pes anserinus pain syndrome, Polio, Polymyositis, Pyomyositis, Repetitive strain injury, Rhizomelic pseudopolyarthritis, Rippling muscle disease , Tumor-induced osteomalacia
Neurologic Amyotrophic lateral sclerosis, familial type 1, Chronic fatigue syndrome, Devic’s disease, Eosinophilia myalgia syndrome, Mitochondrial myopathy, Mixed connective tissue disease, Multiple sclerosis, Myalgic encephalomyelitis, Optic neuropathy, Peripheral neuropathy, Pes anserinus pain syndrome, Stiff man syndrome, Sweet’s disease, West nile encephalitis, Western equine encephalitis
Nutritional/Metabolic Hypovitaminosis d, Phosphate diabetes , Vitamin d deficiency
Obstetric/Gynecologic No underlying causes
Oncologic Tumor-induced osteomalacia
Ophthalmologic Acute posterior multifocal placoid pigment , Optic neuropathy, Stickler syndrome
Overdose/Toxicity Alcohol withdrawal, Barbiturate withdrawal, Caffeine withdrawal, Corticosteroid withdrawal, Etidronic acid, Glucocorticoid-induced myopathy, Opiate withdrawal
Psychiatric Stress
Pulmonary Coccidioidomycosis , Hiv, Legionellosis, Pneumonia, Sarcoidosis, Severe acute respiratory syndrome, Viral pneumonia
Renal/Electrolyte Haff syndrome, Hypokalemia, Rhabdomyolysis
Rheumatology/Immunology/Allergy Bursitis, Chronic exertional compartment syndrome, Dermatomyositis, Devic’s disease, Eosinophilia myalgia syndrome, Febuxostat, Fibromyalgia, Hibernian fever, Inflammatory myopathy, Polyarteritis nodosa, Polymyalgia rheumatica, Polymyositis, Sarcoidosis, Stickler syndrome, Systemic lupus erythematosus
Sexual Aids, Herpes
Trauma Physical trauma, Repetitive strain injury
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. ↑ MedlinePlus

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Differentiating Myalgia from other Diseases

Differentiating Myalgia from other Diseases

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References

Natural History, Complications and Prognosis

Natural History, Complications and Prognosis

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References

Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Other Imaging Studies | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention

Related Chapters

de:Myalgie id:Myalgia it:Mialgia nl:Spierpijn

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]